Carbimazole (Neo-Mercazole) in Thyrotoxicosis

Carbimazole--resistant thyrotoxicosis.

Treatment of thyrotoxicosis resistant to carbimazole with corticosteroids.

We report two patients whose thyrotoxicosis failed to respond to conventional treatment with carbimazole. The patients remained persistently hyperthyroid, both clinically and biochemically, despite several months of carbimazole therapy at the maximum recommended doses. Prednisolone 20 mg per day was then given in addition to the antithyroid drug and a dramatic response observed in both cases. T...

Effect of pretreatment with carbimazole in patients with thyrotoxicosis subsequently treated with radioactive iodine.

Preliminary treatment with carbimazole in a series of 181 patients with thyrotoxicosis selected for treatment with radioactive iodine did not make any significant difference to the subsequent response to (131)I therapy.

Carbimazole Induced Pleural Effusion: A Case Report

Objective. To describe a patient with unilateral exudative pleural effusion that developed after commencement of carbimazole. Methods. We describe the presentation and clinical journey of an elderly woman who presented to the chest physicians initially with pleural effusion but was followed up by the endocrinology team. Result. The patient was a 77-year-old Caucasian woman who presented with sy...

Electrically heated gloves for intermittent digital ischaemia.

et al.4 Moreover, because of its slow elimination amiodarone would inhibit uptake of radioactive iodine for months. Although amiodarone has been reported to cause thyrotoxicosis, this appears to be rare,3 probably occurring only in subjects with associated iodine deficiency (Jod-Basedow effect). Thus amiodarone controls thyrotoxicosis clinically and biochemically but has no advantages over equi...